Experiments have been done on female mice with the hormone php to determine possible reasons for stress in adolescents. This " crazy hormone "effect maybe caused by THP paradoxical effect on teenagers as opposed to adults.

The magazine " Nature Neuroscience ".reports its finding that may shed new light on adolescent suicidal tendencies that have typically been explained as just growing up stress and less as anything hormonal. There may be some very practical implactions to this seemingly revolutionary discovery. Very specific hormonal therapy can be used to help teens that up to till now were taking over the counter anti-depressments that often are counterproductive.